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Given potential for viral infection/reactivation to cause or exacerbate DRESS, the authors currently advise testing HHV6, HHV7, CMV, and EBV viral loads via PCR from peripheral blood at the time of diagnosis/initial work-up, and if negative, perform repeat testing if the patient’s disease is recalcitrant to systemic immunosuppressive treatment (for consideration of antiviral therapy)
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