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Furthermore, the enzyme activity of NuP was detected in mung bean ( Vigna radiata ) (Matsui and Ashihara, 2008), and the enzyme activity of NicRiD was detected in potato (Katahira and Ashihara, 2009)

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An estimated 3-12% of people treated with opioids for chronic pain will develop an addiction or abuse with negative consequences.(12) Approximately 8.6 million Americans reported misusing prescription opioids in 2023.(13) People who develop tolerance or dependence to prescription opioids may transition to illegally produced opioids, such as a fentanyl