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[9] Deep intramuscular administration into the gluteal muscle using a 22-gauge needle is recommended, and patients who self-inject must be trained in aseptic technique, site rotation and safe sharps disposal to reduce infection and tissue-injury risk
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![These highlights do not include all the information needed to use ADVATE® safely and effectively. See full prescribing information for ADVATE. ADVATE [antihemophilic factor (recombinant)] lyophilized powder for reconstitution, for intravenous injection](https://dailymed.nlm.nih.gov/dailymed/image.cfm?name=advate-40.jpg&id=870896)
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