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When phorbol 12-myristate 13-acetate (PMA)–treated human liver cancer cell lines (HepG2 and Hep3B) were incubated with 6G, the activity of matrix metalloproteinase-9 (MMP-9) was reduced, while an increase in the expression of tissue inhibitor metalloproteinase-1 (TIMP-1) protein was observed in both cell lines
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This pathway is known to be aberrantly activated in endometriosis (Fig
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