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In the case of the JNK inhibitor SP600125, which is only soluble in DMSO and requires early treatment, 70% of the protection against APAP toxicity was caused by DMSO and 30% by SP600125 [36]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 89.Xu L, Liu Y, Chen X, Zhong H, Wang Y