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In two ethnically Irish populations, one of young adults and another of adults ≥60, two different polymorphisms were found to increase MMA levels

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1 Introduction High-altitude environments are defined by hypobaric hypoxia, and rapid exposure to such conditions without adequate acclimatization can induce a cascade of physiological responses such as dyspnea and headache, which may progress into life-threatening acute high-altitude illness (AHAI)