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Inhibition of iNOS, which is elevated in retinal glia of diabetic animal models, rescued functional hyperemia, possibly by attenuating EET production (Mishra and Newman, 2010)

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Other inhibitors of mTOR namely everolimus (PubChem CID: 6442177), temsirolimus (PubChem CID: 6918289) and sirolimus (PubChem CID: 46835353) were assessed in single-agent clinical trials