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Importantly, the biphasic regulation of phase-separated condensates by ATP is critical for maintaining the health of the RPE by promoting both optimal phase separation and preventing the aggregation of pathological proteins (112, 113)

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α-tocopherol, a potent active hydrolysis product of vitamin E, can prevent PUFA-induced lipid peroxidation, cytokine production, and neutrophil infiltration, to some extent, inhibiting cell ferroptosis [276]