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Jing Xing, Michigan State University, United States Updates Copyright © 2022 Balderas-Vazquez, Bernal-Morales, Garcia-Montalvo, Vega, Herrera-Huerta, Rodríguez-Landa, Velázquez-Hernández, Xotlanihua-Gervacio and Valenzuela
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After cisplatin enters cells, it acts on the cytochrome P450 (CYP450) enzymatic system on the endoplasmic reticulum membrane to induce oxidative stress and activate caspase-12, which leads to apoptosis [43]
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