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Infarct Size Reduction In a rat left-anterior-descending (LAD) coronary ligation model, BPC-157 administered intraperitoneally at 10 mcg/kg immediately before reperfusion reduced infarct size (as a percentage of area at risk) from approximately 52% in controls to approximately 31% in treated animals, roughly a 40% relative reduction

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The two pathways are not redundant, which is the rational basis for combining them