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Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system… [PMID: 35087020] Laboratory literature summary: Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38(+)…
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A previous limitation of the metalloporphyrin class of compounds has been their poor oral bioavailability, but several compounds in the AEOL 112-series have been shown to have good oral bioavailability and longer plasma half-lives which should make them better candidates for treating chronic diseases [22]
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