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In order to improve outcomes, biphasic scaffolds can be created with a softer upper layer containing chondrogenic factors (e.g., TGF-β, chondroitin sulfate) and a stiffer lower layer, often loaded with calcium phosphate, hydroxyapatite, or bone morphogenetic protein (BMP), to provide structural support of the above cartilage layer and to promote osteogenic tissue formation and boney integration
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Également connue sous le nom de cobalamine, la vitamine b12 au Maroc est un nutriment essentiel que l’organisme ne fabrique pas lui-même : il doit être apporté par l’alimentation ou par une supplémentation adaptée
