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In addition, comparative genomics analysis revealed that the lignin biosynthesis pathway was overrepresented, and 30 related genes were identified, including PAL , 4CL , CCR , CAD , CCOAOMT , F5H , COMT , and POX (Supplementary Tables S19 and S21, Fig

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Unlike traditional clinical parameters, which primarily reflect historical tissue destruction, oxidative stress biomarkers offer a dynamic snapshot of ongoing biological activity, thereby enabling real-time assessment of disease activity and progression (90)