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However, circulating homocysteine levels are related to plasma creatinine and uric acid concentrations and to sex and age (Brattström et al, 1994

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Though IV and oral NAC loading doses were similar (140-150 mg/kg), the oral NAC regimen provided an additional 70 mg/kg every 4 hours for 17 doses, while the IV NAC regimen provided an additional 12.5 mg/kg/h for 4 hours, followed by 6.25 mg/kg/hr for the next 16 hours