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Electrophysiological and c-Fos mapping studies in rodent models have demonstrated that amylin receptor activation in these regions inhibits gastric emptying, reduces meal size, and activates downstream satiety circuits projecting to the hypothalamic arcuate nucleus (Lutz et al., Physiology & Behavior, 2010)

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Instead of using a one‑size‑fits‑all dosage, a structured approach focuses on safety, proper monitoring, and gradual adjustments based on how the body responds