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Patients should be asked if their pain is worsened with bladder filling (“painful bladder filling”) and/or their strong urge to urinate was due to pain, pressure, or discomfort (“painful urgency”), since these are characteristic symptoms of IC/BPS

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That trial, CedLara, was discontinued in June 2022: a pre-specified interim analysis conducted at roughly half of target enrolment concluded that the number of additional patients required to demonstrate a statistically significant effect was too large to justify continuing