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Genetic loss-of-function studies in humans would clarify causality, but large-scale Mendelian randomization analyses for NNMT have not been prominently published as of this writing
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[DOI] [PubMed] [Google Scholar] Patyra K., Löf C., Jaeschke H., Undeutsch H., Zheng H.S., Tyystjärvi S., Pluawska K., Doroszko M., Chrusciel M., Loo B.M., Kurkijarvi R., Zhang F.P., Hunang C.J., Ohlsson C., Kero A., Poutanen M., Toppari J., Paschke R., Rahman N., Huhtaniemi I., Jaaskelainen J., Kero J