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In addition, FGF21 treatment significantly reduces ACSL4 and iron deposition, increases GPX4 expression, and reduces ferroptosis in nerve cells by activating the FGFR1/β-Klotho pathway

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Patients with a history of suicidal ideation or attempts should be carefully evaluated before initiating treatment with Semaglutide / Cyanocobalamin Injection, as post-marketing reports have described occurrences of suicidal thoughts and behaviors in patients treated with GLP-1 receptor agonists