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In recent years, the composition of membrane FAs, particularly the ratios of saturated FAs (SFAs), MUFAs, and PUFAs in regulating cell survival and lipotoxicity-related ferroptosis has been increasingly appreciated (10–12)

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This suggested that cannabinoids exert an upstream effect on the pituitary’s release of LH, potentially influencing reproduction by acting on the GnRH neurons in the hypothalamus