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As suggested by GPx-1's effect on cell growth and apoptosis reviewed in section IV, GPx-1 overexpression may have an antitumorogenic effect in some cancers theoretically by limiting oxidants (234), whereas it may allow for the survival of transformed cells in other cancers by limiting apoptotic mechanisms (238)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Lin JL, Leu ML, Liu YC, Chen GH