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As an underlying mechanism, the membrane lipid microdomain is associated with the kaempferol-mediated beneficial effects on TJ as evidenced by the inhibition of kaempferol-induced elevation of TER after extraction of cholesterol with methyl- β- cyclodextrin and kaempferol-mediated increase in the TJ protein distributions in the cholesterol-rich lipid microdomain [63]
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In-vitro and in-vivo research shows LACCE to exhibit strong antioxidant effects, including protecting skin against UVB induced stress
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