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8-oxoG was shown to activate the ATM/ChK2 pathway within minutes, followed by further activation of p53 signaling, which prevents cell growth and accelerates premature senescence (Barnes et al., 2022)

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Terms such as “cellular rejuvenation,” “age reversal,” “DNA repair,” “life extension,” and “telomere restoration” often combine laboratory observations, animal research, theoretical mechanisms, and marketing language