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COVID-associated severe cases result in complex biological spectacles, such as apoptosis induction, macrophage activation, oxidative tissue damage and higher contents of pro-inflammatory cytokines [18]

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Among the vinca alkaloids, Vincristine (VCR), which is derived from the Madagascar Catharanthus roseus plant, is a primary antineoplastic agent used to treat lymphomas, leukemias, and sarcomas