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Effects of MB and Derivatives on Mitochondria We determined the effect of MB and its derivatives on the activity of mitochondria complexes I-III (NADH oxidase and cytochrome c reductase, respectively) and complexes II-III (succinate dehydrogenase and cytochrome c reductase, respectively)

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This is because each patient’s need for vitamin B12 can vary significantly, depending on the underlying cause of deficiency—such as pernicious anemia, malabsorption disorders, dietary insufficiency, or the use of certain medications