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22 Of 31 patients in the clEDS literature, 5 had experienced frequent subconjunctival hemorrhages and 4/19 patients reported this in our cohort
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Another relevant finding is that double cat2 gr1 mutants, in which GSSG can accumulate to extremely high levels, do not engage the necrotic cell death pathways observed in cat2 , although they do show leaf bleaching in some conditions (Mhamdi et al., 2010a)
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