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Although IRB group (3.836 ± 4.322) exhibited lower Il-6 expression than IR, the reduction was not statistically significant ( p = 0.113)

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SLU-PP-332 is a synthetic small-molecule compound developed as a selective pan-ERR agonist, designed to activate all three Estrogen-Related Receptors — ERRα, ERRβ, and ERRγ — simultaneously