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From these, 48 were selected after title and abstract screening, and only 22 studies met the inclusion criteria: i) healthy population exposed to environmental chemical contaminants, ii) case-control/cohort studies reporting BDNF protein levels, BDNF gene methylation, or SNPs of the BDNF gene, iii) articles published within 10 years, iv) free available full-text article and written in English, and v) scoring ≥7 points in the New-Castle Ottawa Scale (NOS)

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