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Alterations to the mitochondrial dynamic network also result in specific therapeutic susceptibilities, in particular, tumors with increased mitochondrial fragmentation or connectivity are hypersensitive to SMAC mimetics and induce apoptosis by blocking the action of inhibitor of apoptosis proteins (IAPs) (124)
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Without direct, head-to-head comparisons between GHK-Cu, AHK-Cu, and DHK-Cu, the field’s structure–function understanding is lacking
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