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Several transition metal ions can catalyze Fenton and Fenton-like reactions to produce hydroxyl radicals (∙OH) and kill cancer cells in the TME

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Melatonin and its effects on sleep have also been explored in clinical trials for AD, with notable findings related to changes in sleep patterns, although direct cognitive or clinical improvements have yet to be firmly established, likely due to the short-term treatment periods (Meng and Wu, 2023)