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AOD-9604 Food & Supplement Interactions: What to Take and What to Avoid At a glance Drug / AOD-9604 is a modified 16-amino-acid fragment (residues 176-191) of human growth hormone Mechanism / stimulates lipolysis through beta-3 adrenergic pathways without activating the GH receptor [1] Meal timing / inject 30-60 minutes before food to avoid insulin-mediated suppression of fat breakdown Insulin interaction / postprandial insulin elevation directly opposes lipolysis in adipose tissue High-glycemic foods / most likely to blunt AOD-9604 effects due to sharp insulin release Caffeine / may complement lipolytic action but can raise cortisol, which promotes visceral fat storage at high doses Calcium and dairy / no known direct interaction, though high-calcium meals slow gastric emptying Regulatory status / not FDA-approved