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Some practitioners employ intermediate dose increases, such as escalating by 0.25 mg increments rather than doubling doses, to improve tolerance in sensitive patients
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The top three research priorities were found to be (1) understanding the biological mechanism behind PEM and how this can be treated or managed (2), which existing drugs used for other conditions would be useful in treating ME/CFS, and (3) finding accurate and reliable diagnostic testing for ME/CFS
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