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Furthermore, HIF-2α represses the transcription of carnitine palmitoyltransferase 1A (CPT1A), which is responsible for mitochondrial β-oxidation by transporting fatty acids and results in lipid deposition 78
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In another set of experiments, twelve male rats were randomly assigned into 2 groups as follows: control ( n = 6) and treated with the antioxidant vitamin E ( n = 6)
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