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MTHFR C677T polymorphism and colorectal cancer risk in Asians: a meta-analysis of 21 studies

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It was found that DA can inhibit lipopolysaccharide (LPS)-induced activation of NLRP3 inflammasome and subsequent production of caspase-1 and IL-1β in a time- and dose-dependent manner through G protein pathway and β-arrestin–dependent pathway ( Figure 1 )