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Two models of GBM cells and an intracranial xenograft mouse model were used to study GBM cells ferroptosis induced by transfection of small interfering RNAs (siRNAs) targeting C5aR1 and treatment with PMX205 [33], a pharmacological inhibitor of C5aR1
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Tesofensine isn't technically a peptide - it's a small molecule drug that acts as a triple monoamine reuptake inhibitor affecting dopamine, norepinephrine, and serotonin simultaneously
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