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Upon recognition, macrophages undergo proinflammatory polarization and phagocytose of oxidized low density lipoprotein (oxLDL), ultimately leading to proatherogenic cytokine production and the formation of foam cells that contribute to plaque progression 2 (Fig

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Mitochondrial import and accumulation of α-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain